The gut microbiota impacts health, and its disruption is potentially related to multiple diseases, including cancer. This project will generate knowledge on the impact of gut microbiota on cancer
read more
Precision Oncology Ireland is a consortium of 5 Irish Universities, 6 Irish Charities, and 10 companies aiming to develop new diagnostics and therapeutics for the personalised treatment of cancer.
read more
To investigate the role of cancer-related genes among patients with Glioblastoma multiforme, who are and are not extreme responders to chemotherapy; to improve understanding the disease
read more
To develop and coordinate a multi-disciplinary nurse-led survivorship clinic and symptom management pathway which integrates hospital and community services.
read more
This research will analyse blood samples from patients with newly diagnosed small cell lung cancer to risk stratify patients and potentially identify new targeted treatments
read more
Investigating a novel aspect of cancer biology with the potential to improve ovarian patient outcomes. A major challenge in the clinical management of Ovarian Cancer is the high rate of reoccurrence.
read more
Prof Merete Haedersdal in collaboration with Dr Soden are working to develop a more effective method for treating skin cancers, using electroporation.
read more
Breakthrough/Charlie Fell Fellowship recipient's pre-clinical work instrumental in 3 Investigator initiated trials opening soon for pancreatic cancer in Willmott Cancer Institute.
read more
Aim is to further understand personalised disease mechanisms and treatment in Uveal melanoma (UM)
read more
Fiona O'Connell was awarded the Musgrave PhD Scholarship for her project: Radiation Response in Oesophageal Cancer: the role of visceral fat tissue in controlling response through immune-meta
read more
Roisin Cassidy was awarded a Breakthrough PhD Scholarship for her project: Chemosensitisation of oesophageal squamous cell carcinoma using epigenetic modifiers and cytotoxic drug polytherapy.
read more
Eimear Mylod was awarded a Breakthrough PhD Scholarship for her project: Harnessing the power of the immune system to fight obesity associated cancer. This research, is under the supervision
read more
This project is investigating how effective non-toxic compounds in combination with electrochemotherapy are against melanoma, and it is working to understand their effect on a cellular level
read more
Overcoming pancreatic cancer resistance by using electroporation.
read more
Investigation of the impact of a Mindfulness Based Stress Reduction (MBSR) programme on the quality of life of people living with secondary cancer.
read more
In Ireland there is a shortage of dietitians, cancer patients need expert nutritional advice and treatment. Often people with cancer to seek out information themselves.
read more
Lifestyle factors including diet, physical inactivity, smoking and alcohol consumption and high body mass index (BMI) are known to contribute to cancer risk. 42-45% of cancers could be prevented.
read more
The aim of this project is to identify new ways of targeting resistant cancers, so that chemotherapeutic regimes can be improved and recurrent disease eliminated in cancer patients.
read more
We will examine the use of electric pulses to aid in the delivery to drugs to tumour tissue. Short electric pulses have been demonstrated to make tissue temporarily more porous.
read more
Our work will position our drug along a pathway where it could eventually be given to oesophageal patients alongside standard CRT to make tumours respond and result in better outcomes for these ca
read more
The development of evidence based resources for cancer patients to help with improving their oral intake during treatment and supporting patient recovery in the survival stage.
read more
Epigenetic therapy is being studied as a way to alter cancer cell growth, migration, and increased sensitivity to cytotoxic drugs for the treatment of oesophageal cancer.
read more
EValuation of the impact of emotional, nutritional & physical exercise support interventions delivered by a volunteer-led Cancer Support centre, on unmet needs & health related QOL of cancer patients.
read more
This project proposes to expand upon treatment regimens of poor prognosis cancers by developing the electroporation treatment of osteosarcoma cancer.
read more
This project evaluates the effect of stemness and resistance to electroporation delivered treatments in relation to pancreatic cancer
read more
A novel treatment regime, which could lead to the induction of both autophagy and differentiation in cells derived from Acute Myeloid Leukaemia (AML)has been identified
read more
Investigating resistance mechanisms in oesophageal cancer cells has shown that a recycling process within cancer cells (called Autophagy) can help cells recover from chemotherapy.
read more
Deeper understanding of the bacteria that live in our body is enabling identification of i) potential causes of and ii) potential treatments for disease.
read more
Due to the poor survival of women with recurrent, chemoresistant ovarian cancer, Breakthrough believe that a greater understanding of the mechanisms which contribute to this resistance is urgent.
read more
Sign up for the newsletter and receive updates, news, events and stories from the lives you have helped make a difference to.
© Site Designed by Granite Digital
