Breakthrough Cancer Research Donate

Investigation of new biomarkers of treatment response in glioblastoma multiforme (an aggressive brain cancer)

By: Dr Frances Drummond | Posted on: 19 Mar 2020

Investigation of new biomarkers of treatment response in glioblastoma multiforme (an aggressive brain cancer)
Dr Richard Banbury

Start year: 2020

Principal Investigators: Dr Richard Banbury

Host Institution: Cork University Hospital

Cancer type: Glioblastoma multiforme (an aggressive brain cancer)

Linked Breakthrough Research Priorities: 1, 5

 

Every year an estimated 290 malignant tumours of the brain are diagnosed in Ireland.  Glioblastoma multiforme is a very aggressive form of brain cancer. 

 

Only 2%, or 1 in 50 people who get this cancer survive more than 3 years after their diagnosis.  These people who survive are called ‘extreme responders’ i.e. they have had an excellent response to the chemotherapy used as the standard of care for this cancer.

 

The aim of this study is to investigate the role of 324 cancer-related genes among patients with Glioblastoma multiforme, who are extreme responders to chemotherapy and those who are not.

 

Through this research the team hope to improve the understanding of this cancer and also to identify potentially new treatment opportunities for this cancer.

 

More information on Brain cancers in Ireland can be found at the following link;

https://www.ncri.ie/news/article/trends-brain-cancer-ireland-our-latest-report-published

 

 

 

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